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Identification of residues within ligand binding domain 1 (LBD1) of the B. burgdorferi OspC protein required for function in the mammalian environment

Borrelia burgdorferi outer surface protein C (ospC) is required for the establishment of infection in mammals. However, its precise function remains controversial. The biologically active form of OspC appears to be a homodimer. Alpha helix 1 and 1′ of the apposing monomers form a solvent-accessible...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Earnhart, Christopher G., LeBlanc, DeLacy V., Alix, Katie E., Desrosiers, Daniel C., Radolf, Justin D., Marconi, Richard T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917209/
https://ncbi.nlm.nih.gov/pubmed/20199597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2010.07103.x
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