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Development and optimization of OspC chimeritope vaccinogens for Lyme disease.

Experimental Outer surface protein (Osp) C based subunit chimeritope vaccinogens for Lyme disease (LD) were assessed for immunogenicity, ability to elicit antibody (Ab) responses to divergent OspC proteins, and bactericidal activity. Chimeritopes are chimeric epitope based proteins that consist of l...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Izac, Jerilyn R., O’Bier, Nathaniel S., Oliver, Lee D., Camire, Andrew C., Earnhart, Christopher G., LeBlanc Rhodes, DeLacy V., Young, Brandon F., Parnham, Stuart R., Davies, Christopher, Marconi, Richard T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085410/
https://ncbi.nlm.nih.gov/pubmed/31959423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2020.01.027
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