Analysis of the antigenic determinants of the OspC protein of the Lyme disease spirochetes: evidence that the C10 motif is not immunodominant or required to elicit bactericidal antibody responses.

As Ixodes ticks spread to new regions, the incidence of Lyme disease (LD) in companion animals and humans will increase. Preventive strategies for LD in canines center on vaccination and tick control (acaricides). Both subunit and bacterin based LD veterinary vaccines are available. Outer surface pr...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Izac, Jerilyn R., Camire, Andrew C., Earnhart, Christopher G., Embers, Monica E., Funk, Rebecca A., Breitschwerdt, Edward B., Marconi, Richard T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453540/
https://ncbi.nlm.nih.gov/pubmed/30922701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2019.02.007
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