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Assessment of the potential contribution of the highly conserved C-terminal motif (C10) of Borrelia burgdorferi outer surface protein C (OspC) in transmission and infectivity

OspC is produced by all species of the Borrelia burgdorferi sensu lato complex and is required for infectivity in mammals. To test the hypothesis that the conserved C-terminal motif (C10) of OspC is required for function in vivo, a mutant Borrelia burgdorferi strain (B31∷ospCΔC10) was created in whi...

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Detalhes bibliográficos
Publicado no:Pathog Dis
Main Authors: Earnhart, Christopher G., Rhodes, DeLacy V. L., Smith, Alexis A., Yang, Xiuli, Tegels, Brittney, Carlyon, Jason A., Pal, Utpal, Marconi, Richard T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497580/
https://ncbi.nlm.nih.gov/pubmed/24376161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/2049-632X.12119
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