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High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer

INTRODUCTION: HER2 gene amplification and protein overexpression (HER2+) define a clinically challenging subgroup of breast cancer with variable prognosis and response to therapy. Although gene expression profiling has identified an ERBB2 molecular subtype of breast cancer, it is clear that HER2+ tu...

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Détails bibliographiques
Auteurs principaux: Staaf, Johan, Jönsson, Göran, Ringnér, Markus, Vallon-Christersson, Johan, Grabau, Dorthe, Arason, Adalgeir, Gunnarsson, Haukur, Agnarsson, Bjarni A, Malmström, Per-Olof, Johannsson, Oskar Th, Loman, Niklas, Barkardottir, Rosa B, Borg, Åke
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917012/
https://ncbi.nlm.nih.gov/pubmed/20459607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2568
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