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The risk allele of SNP rs3803662 and the mRNA level of its closest genes TOX3 and LOC643714 predict adverse outcome for breast cancer patients

BACKGROUND: The minor allele of SNP rs3803662 has been shown to correlate with increased breast cancer risk and with lower expression of TOX3. The SNP is closely located to TOX3 residing within an uncharacterised gene LOC643714. The aim of the study was to examine the association of the risk allele...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gudmundsdottir, Eydis Th, Barkardottir, Rosa B, Arason, Adalgeir, Gunnarsson, Haukur, Amundadottir, Laufey Th, Agnarsson, Bjarni A, Johannsson, Oskar Th, Reynisdottir, Inga
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553017/
https://ncbi.nlm.nih.gov/pubmed/23270421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-621
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