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Evidence against PALB2 involvement in Icelandic breast cancer susceptibility

Several mutations in the PALB2 gene (partner and localizer of BRCA2) have been associated with an increased risk of breast cancer, including a founder mutation, 1592delT, reported in Finnish breast cancer families. Although most often the risk is moderate, it doesn't exclude families with high-...

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Detalhes bibliográficos
Main Authors: Gunnarsson, Haukur, Arason, Adalgeir, Gillanders, Elizabeth M, Agnarsson, Bjarni A, Johannesdottir, Gudrun, Johannsson, Oskar Th, Barkardottir, Rosa B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491591/
https://ncbi.nlm.nih.gov/pubmed/18637200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5751-7-5
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