Neutralization of Human Respiratory Syncytial Virus Infectivity by Antibodies and Low-Molecular-Weight Compounds Targeted against the Fusion Glycoprotein

Human respiratory syncytial virus (HRSV) fusion (F) protein is an essential component of the virus envelope that mediates fusion of the viral and cell membranes, and, therefore, it is an attractive target for drug and vaccine development. Our aim was to analyze the neutralizing mechanism of anti-F a...

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Hlavní autoři: Magro, Margarita, Andreu, David, Gómez-Puertas, Paulino, Melero, José A., Palomo, Concepción
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916552/
https://ncbi.nlm.nih.gov/pubmed/20534864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00447-10
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