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A Novel Motif in HIV-1 Nef That Regulates MIP-1β Chemokine Release in Macrophages

All primate lentiviruses encode Nef, an accessory protein that is important for viral pathogenicity in vivo. Lentiviral Nef proteins regulate the release of chemokines (MIP-1 α/β) from infected macrophages, thereby enhancing virus dissemination (S. Swingler, A. Mann, J. Jacque, B. Brichacek, V. G. S...

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Main Authors: Dai, Lue, Stevenson, Mario
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916519/
https://ncbi.nlm.nih.gov/pubmed/20504918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00741-10
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