Gfi1 Expression Is Controlled by Five Distinct Regulatory Regions Spread over 100 Kilobases, with Scl/Tal1, Gata2, PU.1, Erg, Meis1, and Runx1 Acting as Upstream Regulators in Early Hematopoietic Cells

The growth factor independence 1 (Gfi1) gene was originally discovered in the hematopoietic system, where it functions as a key regulator of stem cell homeostasis, as well as neutrophil and T-cell development. Outside the blood system, Gfi1 is essential for inner-ear hair and intestinal secretory ce...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Wilson, Nicola K., Timms, Richard T., Kinston, Sarah J., Cheng, Yi-Han, Oram, S. Helen, Landry, Josette-Renee, Mullender, Joanne, Ottersbach, Katrin, Gottgens, Berthold
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916401/
https://ncbi.nlm.nih.gov/pubmed/20516218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00032-10
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi