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Adaptive Resistance to the “Last Hope” Antibiotics Polymyxin B and Colistin in Pseudomonas aeruginosa Is Mediated by the Novel Two-Component Regulatory System ParR-ParS

As multidrug resistance increases alarmingly, polymyxin B and colistin are increasingly being used in the clinic to treat serious Pseudomonas aeruginosa infections. In this opportunistic pathogen, subinhibitory levels of polymyxins and certain antimicrobial peptides induce resistance toward higher,...

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Bibliografske podrobnosti
Main Authors: Fernández, Lucía, Gooderham, W. James, Bains, Manjeet, McPhee, Joseph B., Wiegand, Irith, Hancock, Robert E. W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916309/
https://ncbi.nlm.nih.gov/pubmed/20547815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00242-10
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