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The Two-Component System CprRS Senses Cationic Peptides and Triggers Adaptive Resistance in Pseudomonas aeruginosa Independently of ParRS

Cationic antimicrobial peptides pass across the outer membrane by interacting with negatively charged lipopolysaccharide (LPS), leading to outer membrane permeabilization in a process termed self-promoted uptake. Resistance can be mediated by the addition of positively charged arabinosamine through...

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Detalhes bibliográficos
Main Authors: Fernández, Lucía, Jenssen, Håvard, Bains, Manjeet, Wiegand, Irith, Gooderham, W. James, Hancock, Robert E. W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497197/
https://ncbi.nlm.nih.gov/pubmed/23006746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01530-12
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