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The Two-Component System CprRS Senses Cationic Peptides and Triggers Adaptive Resistance in Pseudomonas aeruginosa Independently of ParRS

Cationic antimicrobial peptides pass across the outer membrane by interacting with negatively charged lipopolysaccharide (LPS), leading to outer membrane permeabilization in a process termed self-promoted uptake. Resistance can be mediated by the addition of positively charged arabinosamine through...

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Autors principals: Fernández, Lucía, Jenssen, Håvard, Bains, Manjeet, Wiegand, Irith, Gooderham, W. James, Hancock, Robert E. W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497197/
https://ncbi.nlm.nih.gov/pubmed/23006746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01530-12
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