Effects of Four Different Meal Types on the Population Pharmacokinetics of Single-Dose Rifapentine in Healthy Male Volunteers

Rifapentine and its primary metabolite, 25-desacetyl rifapentine, are active against mycobacterium tuberculosis. The objectives of this study were to describe the population pharmacokinetics of rifapentine and 25-desacetyl rifapentine in fasting and fed states. Thirty-five male healthy volunteers we...

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Detalhes bibliográficos
Main Authors: Zvada, Simbarashe P., Van Der Walt, Jan-Stefan, Smith, Peter J., Fourie, P. Bernard, Roscigno, Giorgio, Mitchison, Denis, Simonsson, Ulrika S. H., McIlleron, Helen M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916304/
https://ncbi.nlm.nih.gov/pubmed/20516273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00345-10
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