CD4 T-Cell Suppression by Cells from Toxoplasma gondii-Infected Retinas Is Mediated by Surface Protein PD-L1

In the inflamed retina, CD4(+) T cells can cause retinal damage when they are not properly regulated. Since tissue expression of major histocompatibility complex (MHC) class II and costimulatory molecules is a key mechanism for regulating effector T cells, we tested the hypothesis that upregulation...

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Detalhes bibliográficos
Main Authors: Charles, Elizabeth, Joshi, Sunil, Ash, John D., Fox, Barbara A., Farris, A. Darise, Bzik, David J., Lang, Mark L., Blader, Ira J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916285/
https://ncbi.nlm.nih.gov/pubmed/20498261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00117-10
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