ANGIOTENSIN II-INDUCED VASCULAR SMOOTH MUSCLE CELL MIGRATION AND GROWTH ARE MEDIATED BY CYTOCHROME P450 1B1-DEPENDENT SUPEROXIDE GENERATION

Cytochrome P450 1B1, expressed in vascular smooth muscle cells, can metabolize arachidonic acid in vitro into several products including 12- and 20-hydroxyeicosatetraenoic acids that stimulate vascular smooth muscle cell growth. This study was conducted to determine if cytochrome P450 1B1 contribute...

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Detalhes bibliográficos
Main Authors: Yaghini, Fariborz A., Song, Chi Young, Lavrentyev, Eduard N., Ghafoor, Hafiz U. B., Fang, Xiao R., Estes, Anne M., Campbell, William B., Malik, Kafait U.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916227/
https://ncbi.nlm.nih.gov/pubmed/20439821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.150029
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