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Prostaglandins Inhibit Cytochrome P450 4A Activity and Contribute to Endotoxin-Induced Hypotension in Rats via Nitric Oxide Production
Increased production of nitric oxide (NO) and prostaglandins contribute to development of hypotension during endotoxemia. We have previously demonstrated that endotoxemia-induced increase in NO production suppresses renal cytochrome P450 (CYP) 4A expression and activity, and that selective inhibitio...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2684946/ https://ncbi.nlm.nih.gov/pubmed/18704327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12272-001-1238-x |
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