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Heat shock protein 90 protects rat mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis via the PI3K/Akt and ERK1/2 pathways

Mesenchymal stem cell (MSC) transplantation has shown a therapeutic potential to repair the ischemic and infracted myocardium, but the effects are limited by the apoptosis and loss of donor cells in host cardiac microenvironment. The aim of this study is to explore the cytoprotection of heat shock p...

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Bibliografske podrobnosti
Main Authors: Gao, Feng, Hu, Xin-yang, Xie, Xiao-jie, Xu, Qi-yuan, Wang, Ya-ping, Liu, Xian-bao, Xiang, Mei-xiang, Sun, Yong, Wang, Jian-an
Format: Artigo
Jezik:Inglês
Izdano: Zhejiang University Press 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916094/
https://ncbi.nlm.nih.gov/pubmed/20669351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1001007
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