Angiopoietin-Like 4 Confers Resistance to Hypoxia/Serum Deprivation-Induced Apoptosis through PI3K/Akt and ERK1/2 Signaling Pathways in Mesenchymal Stem Cells

Angiopoietin-like 4 (ANGPTL4) is a potential anti-apoptotic agent for various cells. We examined the protective effect of ANGPTL4 on hypoxia/serum deprivation (SD)-induced apoptosis of MSCs, as well as the possible mechanisms. MSCs were obtained from rat bone marrow and cultured in vitro. Apoptosis...

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Detalhes bibliográficos
Main Authors: Hou, Meng, Cui, Jinjin, Liu, Jingjin, Liu, Fang, Jiang, Rui, Liu, Kai, Wang, Yongshun, Yin, Li, Liu, Wenhua, Yu, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897528/
https://ncbi.nlm.nih.gov/pubmed/24465718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085808
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