Heat shock protein 90β inhibits apoptosis of intestinal epithelial cells induced by hypoxia through stabilizing phosphorylated Akt

Intestinal epithelial cell (IEC) apoptosis induced by hypoxia compromise intestinal epithelium barrier function. Both Akt and Hsp90 have cytoprotective function. However, the specific role of Akt and Hsp90β in IEC apoptosis induced by hypoxia has not been explored. We confirmed that hypoxia-induced...

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Detalhes bibliográficos
Main Authors: Zhang, Shuai, Sun, Yong, Yuan, Zhiqiang, Li, Ying, Li, Xiaolu, Gong, Zhenyu, Peng, Yizhi
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133828/
https://ncbi.nlm.nih.gov/pubmed/23351384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2013.46.1.037
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