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Radicals in the Reaction between Peroxynitrite and Uric Acid Identified by Electron Spin Resonance Spectroscopy and Liquid Chromatography Mass Spectrometry

Peroxynitrite is a reactive oxidant produced in vivo in response to oxidative and other stress by the diffusion-limited reaction of nitric oxide and superoxide. This contribution is focused on the identification of free radical intermediates of uric acid formed during its reaction with peroxynitrite...

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Detalhes bibliográficos
Main Authors: Imaram, Witcha, Gersch, Christine, Kim, Kyung Mee, Johnson, Richard J., Henderson, George N., Angerhofer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916040/
https://ncbi.nlm.nih.gov/pubmed/20406679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.04.010
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