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Simultaneous determination of uric acid metabolites allantoin, 6-aminouracil, and triuret in human urine using liquid chromatography–mass spectrometry

Uric acid (UA) can be directly converted to allantoin enzymatically by uricase in most mammals except humans or by reaction with superoxide. UA can react directly with nitric oxide to generate 6-aminouracil and with peroxynitrite to yield triuret; both of these metabolites have been identified in bi...

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Dettagli Bibliografici
Autori principali: Kim, Kyung Mee, Henderson, George N., Frye, Reginald F., Galloway, Cheryl D., Brown, Nancy J., Segal, Mark S., Imaram, Witcha, Angerhofer, Alexander, Johnson, Richard J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684329/
https://ncbi.nlm.nih.gov/pubmed/19081307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2008.11.029
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