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Structural Determinants of Photoreactivity of Triplex Forming Oligonucleotides Conjugated to Psoralens
Triplex-forming oligonucleotides (TFOs) with both DNA and 2′-O-methyl RNA backbones can direct psoralen photoadducts to specific DNA sequences. However, the functional consequences of these differing structures on psoralen photoreactivity are unknown. We designed TFO sequences with DNA and 2′-O-meth...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
SAGE-Hindawi Access to Research
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2915845/ https://ncbi.nlm.nih.gov/pubmed/20725628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/523498 |
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