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TNFα-Induced Sickness Behavior in Mice with Functional 55 kD TNF Receptors is Blocked by Central IGF-I
A variety of pathogenic insults cause synthesis of tumor necrosis factor (TNF)α in the brain, resulting in sickness behavior. Here we used TNF-receptor (TNF-R)2-deficient and wild-type mice to demonstrate that the reduction in social exploration of a novel juvenile, the increase in immobility and th...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2915825/ https://ncbi.nlm.nih.gov/pubmed/17512609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.04.011 |
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