TNFα-Induced Sickness Behavior in Mice with Functional 55 kD TNF Receptors is Blocked by Central IGF-I

A variety of pathogenic insults cause synthesis of tumor necrosis factor (TNF)α in the brain, resulting in sickness behavior. Here we used TNF-receptor (TNF-R)2-deficient and wild-type mice to demonstrate that the reduction in social exploration of a novel juvenile, the increase in immobility and th...

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Bibliographic Details
Main Authors:	Palin, Karine, Bluthé, Rose-Marie, McCusker, Robert H., Moos, Françoise, Dantzer, Robert, Kelley, Keith W.
Format:	Artigo
Language:	Inglês
Published:	2007
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2915825/ https://ncbi.nlm.nih.gov/pubmed/17512609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.04.011
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TNFα-Induced Sickness Behavior in Mice with Functional 55 kD TNF Receptors is Blocked by Central IGF-I

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