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The type 1 TNF receptor and its associated adapter protein, FAN, are required for TNF α-induced sickness behavior
RATIONALE: During the course of an infection, the pro-inflammatory cytokine tumor necrosis factor alpha (TNFα) acts in the brain to trigger development of behavioral responses, collectively termed sickness behavior. Biological activities of TNFα can be mediated by TNF receptor type 1 (TNF-R1) and ty...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711641/ https://ncbi.nlm.nih.gov/pubmed/18825372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-008-1331-4 |
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