Novel Activity of an Anti-Inflammatory Cytokine: IL-10 Prevents TNFα-Induced Resistance to IGF-I in Myoblasts

IL-10 is an anti-inflammatory cytokine that suppresses synthesis of proinflammatory cytokines and their receptors. Here we tested the possibility that TNFα-induced hormone resistance in myoblasts might be overcome by IL-10. We found that IL-10 restores myogenesis by suppressing the ability of exogen...

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Hauptverfasser: Strle, Klemen, McCusker, Robert H., Tran, Lynn, King, Alexandra, Johnson, Rodney W., Freund, Gregory G., Dantzer, Robert, Kelley, Keith W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2078530/
https://ncbi.nlm.nih.gov/pubmed/17572510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.05.003
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