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Calcium-dependent Conformational Changes in Inositol Trisphosphate Receptors
We have used limited trypsin digestion and reactivity with PEG-maleimides (MPEG) to study Ca(2+)-induced conformational changes of IP(3)Rs in their native membrane environment. We found that Ca(2+) decreased the formation of the 95-kDa C-terminal tryptic fragment when detected by an Ab directed at a...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2915744/ https://ncbi.nlm.nih.gov/pubmed/20530483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.123208 |
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