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The Small G Protein Rac1 Activates Phospholipase Cδ1 through Phospholipase Cβ2

Rac1, which is associated with cytoskeletal pathways, can activate phospholipase Cβ2 (PLCβ2) to increase intracellular Ca(2+) levels. This increased Ca(2+) can in turn activate the very robust PLCδ1 to synergize Ca(2+) signals. We have previously found that PLCβ2 will bind to and inhibit PLCδ1 in so...

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Bibliografiset tiedot
Päätekijät: Guo, Yuanjian, Golebiewska, Urszula, D'Amico, Stephen, Scarlata, Suzanne
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915735/
https://ncbi.nlm.nih.gov/pubmed/20530480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132654
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