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The Small G Protein Rac1 Activates Phospholipase Cδ1 through Phospholipase Cβ2
Rac1, which is associated with cytoskeletal pathways, can activate phospholipase Cβ2 (PLCβ2) to increase intracellular Ca(2+) levels. This increased Ca(2+) can in turn activate the very robust PLCδ1 to synergize Ca(2+) signals. We have previously found that PLCβ2 will bind to and inhibit PLCδ1 in so...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2915735/ https://ncbi.nlm.nih.gov/pubmed/20530480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132654 |
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