Biochemical and Genetic Insights into Asukamycin Biosynthesis

Asukamycin, a member of the manumycin family metabolites, is an antimicrobial and potential antitumor agent isolated from Streptomyces nodosus subsp. asukaensis. The entire asukamycin biosynthetic gene cluster was cloned, assembled, and expressed heterologously in Streptomyces lividans. Bioinformati...

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Autori principali: Rui, Zhe, Petříčková, Kateřina, Škanta, František, Pospíšil, Stanislav, Yang, Yanling, Chen, Chung-Yung, Tsai, Shih-Feng, Floss, Heinz G., Petříček, Miroslav, Yu, Tin-Wein
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915727/
https://ncbi.nlm.nih.gov/pubmed/20522559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.128850
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