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Biochemical and Genetic Insights into Asukamycin Biosynthesis

Asukamycin, a member of the manumycin family metabolites, is an antimicrobial and potential antitumor agent isolated from Streptomyces nodosus subsp. asukaensis. The entire asukamycin biosynthetic gene cluster was cloned, assembled, and expressed heterologously in Streptomyces lividans. Bioinformati...

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Detalhes bibliográficos
Main Authors: Rui, Zhe, Petříčková, Kateřina, Škanta, František, Pospíšil, Stanislav, Yang, Yanling, Chen, Chung-Yung, Tsai, Shih-Feng, Floss, Heinz G., Petříček, Miroslav, Yu, Tin-Wein
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915727/
https://ncbi.nlm.nih.gov/pubmed/20522559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.128850
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