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N-methylation of the Amide Bond by Methyltransferase Asm10 in Ansamitocin Biosynthesis
Ansamitocins are potent antitumor agents produced by Actinosynnema pretiosum. As deduced from their structures, an N-methylation on the amide bond is required among the various modifications. The encoded protein by asm10 belongs to SAM-dependent methyltransferase family. Through gene inactivation an...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3391011/ https://ncbi.nlm.nih.gov/pubmed/21681880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201100062 |
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