Two Golgi-resident 3′-Phosphoadenosine 5′-Phosphosulfate Transporters Play Distinct Roles in Heparan Sulfate Modifications and Embryonic and Larval Development in Caenorhabditis elegans

Synthesis of extracellular sulfated molecules requires active 3′-phosphoadenosine 5′-phosphosulfate (PAPS). For sulfation to occur, PAPS must pass through the Golgi membrane, which is facilitated by Golgi-resident PAPS transporters. Caenorhabditis elegans PAPS transporters are encoded by two genes,...

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Detalles Bibliográficos
Autores principales: Dejima, Katsufumi, Murata, Daisuke, Mizuguchi, Souhei, Nomura, Kazuko H., Izumikawa, Tomomi, Kitagawa, Hiroshi, Gengyo-Ando, Keiko, Yoshina, Sawako, Ichimiya, Tomomi, Nishihara, Shoko, Mitani, Shohei, Nomura, Kazuya
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Glycobiology and Extracellular Matrices
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915708/
https://ncbi.nlm.nih.gov/pubmed/20529843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.088229
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