The ortholog of human solute carrier family 35 member B1 (UDP-galactose transporter-related protein 1) is involved in maintenance of ER homeostasis and essential for larval development in Caenorhabditis elegans

Although the solute carrier 35B1 (SLC35B1) is evolutionarily conserved, its functions in metazoans remain unknown. To elucidate its function, we examined developmental roles of an SLC35B1 family gene (HUT-1: homolog of UDP-Gal transporter) in Caenorhabditis elegans. We isolated a deletion mutant of...

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Autors principals: Dejima, Katsufumi, Murata, Daisuke, Mizuguchi, Souhei, Nomura, Kazuko H., Gengyo-Ando, Keiko, Mitani, Shohei, Kamiyama, Shin, Nishihara, Shoko, Nomura, Kazuya
Format: Artigo
Idioma:Inglês
Publicat: The Federation of American Societies for Experimental Biology 2009
Matèries:
Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704591/
https://ncbi.nlm.nih.gov/pubmed/19270184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-123737
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