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Cutting Edge: CTLA-4–B7 Interaction Suppresses Th17 Cell Differentiation

Th cells that produce IL-17 (Th17 cells) are a distinct subset of Th cells implicated in several autoimmune diseases. Although CD28–B7 interaction has been shown to be involved in Th17 differentiation in vitro, the role of CTLA-4 in controlling Th17 development is completely unknown. We report in th...

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Detalhes bibliográficos
Main Authors: Ying, Haiyan, Yang, Lifen, Qiao, Guilin, Li, Zhenping, Zhang, Li, Yin, Fei, Xie, Dong, Zhang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915549/
https://ncbi.nlm.nih.gov/pubmed/20601598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903369
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