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Program Death-1 Regulates Peripheral T Cell Tolerance via an Anergy-Independent Mechanism

Program Death-1 (PD-1) has been documented to negatively regulate immune responses. However, the cellular and molecular mechanisms for PD-1-mediated immune suppression have not been fully elucidated. In this study, we show that loss of PD-1 does not lead to defective induction of CD4(+) T cell anerg...

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Detalhes bibliográficos
Main Authors: Qiao, Guilin, Yang, Lifen, Li, Zhenping, Ying, Haiyan, Hassen, Yassir, Yin, Fei, Zhang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327760/
https://ncbi.nlm.nih.gov/pubmed/22459706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2012.02.006
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