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CD40 Ligation Decreases its Protein Half-Life at the Cell Surface
CD40 is expressed on a variety of tumors; anti-CD40 agonists promote tumor cell apoptosis and subsequent tumor regression. Because the effectiveness of anti-CD40-agonists is dependent upon CD40 surface expression, the current study examined ligation-mediated changes in CD40 protein half-life (t(1/2)...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2915443/ https://ncbi.nlm.nih.gov/pubmed/18253927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737828 |
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