A Polymorphic Variant of AFAP-110 Enhances cSrc Activity

Enhanced expression and activity of cSrc are associated with ovarian cancer progression. Generally, cSrc does not contain activating mutations; rather, its activity is increased in response to signals that affect a conformational change that releases its autoinhibition. In this report, we analyzed o...

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Main Authors: Clump, David A, Yu, Jing Jie, Cho, YoungJin, Gao, Rui, Jett, John, Zot, Henry, Cunnick, Jess M, Snyder, Brandi, Clump, Anne C, Dodrill, Melissa, Gannett, Peter, Coad, James E, Shurina, Robert, Figg, W Douglas, Reed, Eddie, Flynn, Daniel C
格式: Artigo
語言:Inglês
出版: Neoplasia Press Inc. 2010
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915419/
https://ncbi.nlm.nih.gov/pubmed/20689769
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