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Actin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary gland

Actin filament-associated protein 1 (AFAP1) is an adaptor protein of cSrc that binds to filamentous actin and regulates the activity of this tyrosine kinase to affect changes to the organization of the actin cytoskeleton. In breast and prostate cancer cells, AFAP1 has been shown to regulate cellular...

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Bibliografiska uppgifter
I publikationen:Oncogene
Huvudupphovsmän: Cunnick, Jess M, Kim, Stephanie, Hadsell, James, Collins, Stephen, Cerra, Carmine, Reiser, Patti, Flynn, Daniel C, Cho, Youngjin
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302073/
https://ncbi.nlm.nih.gov/pubmed/25043309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.205
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