A Polymorphic Variant of AFAP-110 Enhances cSrc Activity

Enhanced expression and activity of cSrc are associated with ovarian cancer progression. Generally, cSrc does not contain activating mutations; rather, its activity is increased in response to signals that affect a conformational change that releases its autoinhibition. In this report, we analyzed o...

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Hauptverfasser: Clump, David A, Yu, Jing Jie, Cho, YoungJin, Gao, Rui, Jett, John, Zot, Henry, Cunnick, Jess M, Snyder, Brandi, Clump, Anne C, Dodrill, Melissa, Gannett, Peter, Coad, James E, Shurina, Robert, Figg, W Douglas, Reed, Eddie, Flynn, Daniel C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2010
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915419/
https://ncbi.nlm.nih.gov/pubmed/20689769
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