A Polymorphic Variant of AFAP-110 Enhances cSrc Activity

Enhanced expression and activity of cSrc are associated with ovarian cancer progression. Generally, cSrc does not contain activating mutations; rather, its activity is increased in response to signals that affect a conformational change that releases its autoinhibition. In this report, we analyzed o...

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Bibliografiska uppgifter
Huvudupphovsmän: Clump, David A, Yu, Jing Jie, Cho, YoungJin, Gao, Rui, Jett, John, Zot, Henry, Cunnick, Jess M, Snyder, Brandi, Clump, Anne C, Dodrill, Melissa, Gannett, Peter, Coad, James E, Shurina, Robert, Figg, W Douglas, Reed, Eddie, Flynn, Daniel C
Materialtyp: Artigo
Språk:Inglês
Publicerad: Neoplasia Press Inc. 2010
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915419/
https://ncbi.nlm.nih.gov/pubmed/20689769
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