A Polymorphic Variant of AFAP-110 Enhances cSrc Activity

Enhanced expression and activity of cSrc are associated with ovarian cancer progression. Generally, cSrc does not contain activating mutations; rather, its activity is increased in response to signals that affect a conformational change that releases its autoinhibition. In this report, we analyzed o...

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書誌詳細
主要な著者: Clump, David A, Yu, Jing Jie, Cho, YoungJin, Gao, Rui, Jett, John, Zot, Henry, Cunnick, Jess M, Snyder, Brandi, Clump, Anne C, Dodrill, Melissa, Gannett, Peter, Coad, James E, Shurina, Robert, Figg, W Douglas, Reed, Eddie, Flynn, Daniel C
フォーマット: Artigo
言語:Inglês
出版事項: Neoplasia Press Inc. 2010
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915419/
https://ncbi.nlm.nih.gov/pubmed/20689769
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