A Polymorphic Variant of AFAP-110 Enhances cSrc Activity

Enhanced expression and activity of cSrc are associated with ovarian cancer progression. Generally, cSrc does not contain activating mutations; rather, its activity is increased in response to signals that affect a conformational change that releases its autoinhibition. In this report, we analyzed o...

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Bibliografiske detaljer
Main Authors: Clump, David A, Yu, Jing Jie, Cho, YoungJin, Gao, Rui, Jett, John, Zot, Henry, Cunnick, Jess M, Snyder, Brandi, Clump, Anne C, Dodrill, Melissa, Gannett, Peter, Coad, James E, Shurina, Robert, Figg, W Douglas, Reed, Eddie, Flynn, Daniel C
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915419/
https://ncbi.nlm.nih.gov/pubmed/20689769
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