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Identifying Cellular Pathways Modulated by Drosophila Palmitoyl-protein Thioesterase 1 Function

Infantile-onset Neuronal Ceroid Lipofuscinosis (INCL) is a severe pediatric neurodegenerative disorder produced by mutations in the gene encoding palmitoyl-protein thioesterase 1 (Ppt1). This enzyme is responsible for the removal of a palmitate post-translational modification from an unknown set of...

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Main Authors: Saja, Stephanie, Buff, Haley, Smith, Alexis C., Williams, Tiffany S., Korey, Christopher A.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914843/
https://ncbi.nlm.nih.gov/pubmed/20206262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.02.010
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