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Genetic Modifiers of Drosophila Palmitoyl–Protein Thioesterase 1-Induced Degeneration
Infantile neuronal ceroid lipofuscinosis (INCL) is a pediatric neurodegenerative disease caused by mutations in the human CLN1 gene. CLN1 encodes palmitoyl–protein thioesterase 1 (PPT1), suggesting an important role for the regulation of palmitoylation in normal neuronal function. To further elucida...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Copyright © 2007 by the Genetics Society of America
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1893024/ https://ncbi.nlm.nih.gov/pubmed/17409080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.067983 |
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