DNA repair polymorphisms and outcome of chemotherapy for acute myelogenous leukemia: a report from the Children’s Oncology Group

Polymorphisms of DNA repair genes RAD51 and XRCC3 increase susceptibility to acute myeloid leukemia (AML) in adults, an effect enhanced by deletion of the glutathione-S-transferase M1 (GSTM1) gene. In this study, we genotyped 452 children with de novo AML treated on CCG protocols 2941 and 2961 and c...

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Detalhes bibliográficos
Main Authors: Bhatla, D, Gerbing, RB, Alonzo, TA, Mehta, PA, Deal, K, Elliott, J, Meshinchi, S, Geiger, H, Perentesis, JP, Lange, BJ, Davies, SM
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914507/
https://ncbi.nlm.nih.gov/pubmed/18033323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.leu.2405000
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