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Characterization of a dominant-active STAT that promotes tumorigenesis in Drosophila
Little is known about the molecular mechanisms by which STAT proteins promote tumorigenesis. Drosophila is an ideal system for investigating this issue, as there is a single STAT (Stat92E), and its hyperactivation causes overgrowths resembling human tumors. Here we report the first identification of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2914209/ https://ncbi.nlm.nih.gov/pubmed/20501334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.05.497 |
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