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Characterization of a dominant-active STAT that promotes tumorigenesis in Drosophila

Little is known about the molecular mechanisms by which STAT proteins promote tumorigenesis. Drosophila is an ideal system for investigating this issue, as there is a single STAT (Stat92E), and its hyperactivation causes overgrowths resembling human tumors. Here we report the first identification of...

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Bibliografiska uppgifter
Huvudupphovsmän: Ekas, Laura A., Cardozo, Timothy J., Flaherty, Maria Sol, McMillan, Elizabeth A., Gonsalves, Foster C., Bach, Erika A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914209/
https://ncbi.nlm.nih.gov/pubmed/20501334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.05.497
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