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Pharmacokinetic and Biodistribution Studies of N-(2-Hydroxypropyl)methacrylamide (HPMA) Copolymer-Dexamethasone Conjugates in Adjuvant–induced Arthritis (AA) Rat Model
N-(2-Hydroxypropyl)-methacrylamide (HPMA) copolymer has been found to be arthrotropic (joint-targeting) in adjuvant-induced arthritis (AA) rat model using magnetic resonance imaging (MRI). In this manuscript, we report the quantitative pharmacokinetics and biodistribution (PK/BD) of (125)I-labeled H...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2914173/ https://ncbi.nlm.nih.gov/pubmed/20557133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100132h |
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