Pharmacokinetic and Biodistribution Studies of N-(2-Hydroxypropyl)methacrylamide (HPMA) Copolymer-Dexamethasone Conjugates in Adjuvant–induced Arthritis (AA) Rat Model

N-(2-Hydroxypropyl)-methacrylamide (HPMA) copolymer has been found to be arthrotropic (joint-targeting) in adjuvant-induced arthritis (AA) rat model using magnetic resonance imaging (MRI). In this manuscript, we report the quantitative pharmacokinetics and biodistribution (PK/BD) of (125)I-labeled H...

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Библиографические подробности
Главные авторы: Quan, Ling-dong, Yuan, Fang, Liu, Xin-ming, Huang, Jian-geng, Alnouti, Yazen, Wang, Dong
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914173/
https://ncbi.nlm.nih.gov/pubmed/20557133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100132h
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