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The Apo Riboswitch as a Molecular Hydra
Riboswitches ‘sense’ metabolites but knowledge is sparse for structures without bound ligand. Stoddard et al. (2010) determined an apo riboswitch structure ‘closed’ to metabolite binding. Further SAXS, biochemical and computational analyses support ensemble behavior with interconverting open and clo...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913869/ https://ncbi.nlm.nih.gov/pubmed/20637410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.06.003 |
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