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Base ionization and ligand binding: how small ribozymes and riboswitches gain a foothold in a protein world*

Genome sequencing has produced thousands of non-protein coding (nc)RNA sequences including new ribozymes and riboswitches. Such RNAs are notable for their extraordinary functionality, which entails exquisite folding that culminates in biocatalytic or ligand-binding capabilities. Here we discuss adva...

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Detalhes bibliográficos
Main Authors: Liberman, Joseph A., Wedekind, Joseph E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112304/
https://ncbi.nlm.nih.gov/pubmed/21530235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2011.03.016
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